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教师目录-旧

陈杰

来源: 发布时间 : 2021-09-13 点击量:

   

陈杰

   

学历学位

农学博士

   

教授

导师类别

博士生导师

专业领域

动物遗传育种与繁殖

研究方向

动物分子遗传育种;

畜禽重要经济性状形成的分子机制;

畜禽分子育种技术。

教育与工作经历

教育经历:

1995年,获得南京农业大学学士学位

1998年,获得南京农业大学硕士学位

2003年,获得南京农业大学博士学位

工作经历:

1998年至今,南京农业大学动物科技学院任教

海外学习经历:

2001年,加拿大圭尔夫大学

2004年,德国莱布尼兹家畜研究所

2008年,美国华盛顿州立大学

2016年,英国卡迪夫大学

联系方式

邮箱:jiechen@njau.edu.cn

电话:025-84399269

奖励及荣誉

2010年入选江苏省青蓝工程优秀青年骨干教师培养对象,以及南京农业大学“133重点人才工程优秀骨干教师培养计划。

参加学术团体及任职情况

中国畜牧兽医学会动物遗传育种学分会 理事

中国畜牧兽医学会动物遗传标记学分会 理事

承担科研项目

1.民猪米色脂肪细胞转化机制与特征研究,国家自然科学基金联合基金项目子任务,52万,2021-2024年;

2.MSTN/miR-124a-2/GR通路介导猪肌肉组织特异性调控肌内脂肪细胞分化的机制研究,国家自然科学基金面上项目,59万,2019-2022年;

3.猪优质肉种质资源保护、分子基础挖掘与创新,国家科技支撑计划

课题,482万,2015-2019年;

4.P160基因家族组织特异性调控猪肌内脂肪沉积的分子机制研究,国家自然科学基金面上项目,80万,2013-2016年;

5.优质高繁白羽肉鹅配套的培育与推广,江苏省农业重大新品种创制项目,24万,2017-2021年;

6.鹅产蛋性能分子选育技术研究及应用于扬州鹅高产蛋品系选育研究,江苏省农业科技自主创新资金,30万,2014-2017年;

7.高产优质转基因奶羊新品种培育,农业部转基因生物新品种培育重大专项,50万,2011-2012年;

8.基于全基因组关联分析挖掘猪肌内脂肪含量相关基因的研究,中央高校基本科研业务费专项资金项目,40万,2011-2014年;

9.猪肌内前体脂肪细胞分化特异性调控基因的分离与功能研究,国家自然科学基金青年科学基金项目,20万,2009-2011年。

 

论文论著:

 

1.  Wang Q, Wang Q,  Melak S, Lin X, Wei W, Zhang L, Chen J. A novel c.-652C>T mutation in  UCHL1 gene is associated with the growth performance in Yangzhou goose. Poult  Sci. 2021 Jul;100(7):101089.

2.  Melak S, Wang Q,  Tian Y, Wei W, Zhang L, Elbeltagy A, Chen J. Identification and Validation of  Marketing Weight-Related SNP Markers Using SLAF Sequencing in Male Yangzhou  Geese. Genes. 2021 Aug 3;12(8):1203

3.  Lin Weimin, Tang Yonghang,  Zhao Yuelei, Zhao Jindi, Zhang Lifan, Wei Wei, Chen Jie*, MiR-144-3p  Targets FoxO1 to Reduce Its Regulation of Adiponectin and Promote  Adipogenesis, Frontiers in Genetics, 2020, 11:603144.

4.  Weimin LinHongcheng LiuYonghang TangYuchen WeiJie Chen*. The  development and controversy of competitive endogenous RNA hypothesis in  non-coding genes. Molecular and Cellular Biochemistry, 2020, DOI:  10.1007/s11010-020-03889-2.

5. Hongcheng  Liu#, Wei Wei#, Weimin Lin, Wensai Yu, Wu Luo, Yingfang Niu, Lifan Zhang, Jie  Chen*. miR-32-5p Regulates Lipid Accumulation in Intramuscular Fat of  Erhualian Pigs by Suppressing KLF3, Lipids, 2020, 10(1): 10.1002/lipd.12294.

6. Kaiqing  Liu#, Wensai Yu#, Wei Wei, Xinbao Zhang, Ye Tian, Melak Sherif, Xin Liu, Chao  Dong, Wangjun Wu, Lifan Zhang and Jie Chen*, Melatonin reduces  intramuscular fat deposition by promoting lipolysis and increasing  mitochondrial function, Journal of Lipid Research, 2019, 60(4):767-782.

7. Kaiqing  Liu, Xinbao Zhang, Wei Wei, Xin Liu, Ye Tian, Haiyin Han, Lifan Zhang,  Wangjun Wu and Jie Chen*, Myostatin/SMAD4 signaling-mediated  regulation of miR-124-3p represses glucocorticoid receptor expression and  inhibits adipocyte differentiation, American Journal of  Physiology-Endocrinology and Metabolism,2019, 316(4):E635-E645.

8. Mengyuan  Xia, Wei Wei, Zaohang Jiang, Dandan He, Zhen Li, Shigang Yu, Qiushi Wang,  Honglin Liu and Jie Chen*, A Functional Mutation in KIAA1462 Promoter  Decreases Glucocorticoid Receptor Affinity and Affects Egg-Laying Performance  in Yangzhou Geese, International Journal of Molecular Sciences, 2018,  19,1531.

9. Dandan  He, Zaohang Jiang, Ye Tian, Haiyin Han, Mengyuan Xia, Wei Wei, Lifan Zhang, Jie  Chen*, Genetic variants in IL 15 promoter affect transcription activity  and intramuscular fat deposition in longissimus dorsi muscle of pigs, Animal  Genetics, 2018, 49(1): 19-28.

10. Haiyin  Han, Shuhua Gu, Weiwei Chu, Wenxing Sun, Wei Wei, Xiaoyong Dang, Ye Tian,  Kaiqing Liu, Jie Chen*, miR-17-5p Regulates Differential Expression of  NCOA3 in Pig Intramuscular and Subcutaneous Adipose Tissue, Lipids, 2017,  52(11): 939-949.

11. Wei  Wei#, Wenxing Sun#, Haiyin Han, Weiwei Chu, Lifan Zhang, Jie Chen*,  miR-130a regulates differential lipid accumulation between intramuscular and  subcutaneous adipose tissues of pigs via suppressing PPARG expression, Gene,  2017, 636:23-29.

12. Haiyin  Han, Wei Wei, Weiwei Chu, Kaiqing Liu, Ye Tian, Zaohang Jiang, and Jie  Chen*, Muscle Conditional Medium Reduces Intramuscular Adipocyte  Differentiation and Lipid Accumulation through Regulating Insulin Signaling,  International Journal of Molecular Sciences, 2017, 18(8): 1799.

13. Weiwei  Chu#, Wei Wei#, Haiyin Han, Ying Gao, Kaiqing Liu, Ye Tian, Zaohang Jiang,  Lifan Zhang, Jie Chen*, Muscle-specific downregulation of GR levels  inhibits adipogenesis in porcine intramuscular adipocyte tissue, Scientific  Reports, 2017, 7(1):510.

14. S.  Yu, M. Xia, M. A. Alsiddig, H. Liu, W. Wei*, J. Chen*, Molecular  cloning, alternative splicing and mRNA expression analysis of MAGI1 and its  correlation with laying performance in geese, British Poultry Science, 2017,  58(2):158-165.

15. Wenxing  SunMV  DodsonZaohang  JiangShigang  YuWeiwei  ChuJie  Chen*.  Myostatin inhibits porcine intramuscular preadipocyte differentiation in  vitro. Domestic Animal Endocrinology, 2016,55:25-31

16. Weiwei  Chu, Wei Wei, Shigang Yu, Haiyin Han, Xiaoli Shi, Wenxing Sun, Ying Gao,  Lifan Zhang, Jie Chen*, C2C12 myotubes inhibit the proliferation and  differentiation of 3T3-L1 preadipocytes by reducing the expression of  glucocorticoid receptor gene, Biochemical and Biophysical Research  Communications, 2016, 472(1):68-74.

17. Shigang  Yu, Wei Wei, Mengyuan Xia, Zaohang Jiang, Dandan He, Zhen Li, Haiyin Han,  Weiwei Chu, HongLin Liu, Jie Chen*, Molecular characterization,  alternative splicing and expression analysis of ACSF2 and its correlation  with egg-laying performance in geese, Animal Genetics, 2016, 47(4):451-462.

18. Haoxin  Yang, Jiawen He, Wei Wei, Weiwei Chu, Shigang Yu, Ye Tian, Fengyi Peng,  Hongcheng Liu, Zengkai Zhang, Jie Chen*, The c.-360 T>C mutation  affects PGAM2 transcription activity and is linked with the water holding  capacity of the longissimus lumborum muscle in pigs, Meat Science, 2016,  122:139-144.

19. ShiGang  Yu, WeiWei Chu, LiFan Zhang, HouMing Han, RongXue Zhao, Wei Wu, JiangNing  Zhu, Michael V. Dodson, Wei Wei, HongLin Liu, Jie Chen*,  Identification of Laying-Related SNP Markers in Geese Using RAD Sequencing,  PLoS One, 2015, 10(7): e0131572.

20. Dang  XY, Chu WW, Shi HC, Yu SG, Han HY, Gu SH, Chen J*. Genetic variants in  ABCA1 promoter affect transcription activity and plasma HDL level in pigs.  Cellular and Molecular Life Sciences. Gene, 555(2): 414-420.

 

 

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