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教师目录-旧

王锋

来源: 发布时间 : 2021-06-10 点击量:

   

王锋

 

   

学历学位

研究生学历、农学博士学位

   

教授

导师类别

博士生导师

专业领域

动物遗传育种与繁殖、动物生物工程、养殖

研究方向

动物胚胎工程;动物生殖调控;羊业科学

教育与工作经历

曾在西北农业大学读本科、硕士、博士学位,香港大学动物学系博士后,曾去美国康涅犾格大学与荷兰瓦格宁根大学高访。

目前在南京农业大学动物科技学院任教。

 

联系方式

caeet@njau.edu.cn

奖励及荣誉

二级教授、钟山学者首席教授,师德标兵;主持的《动物繁殖学》分别获首批国家级一流本科课程(2020)及国家精品(2010)、首批精品资源共享课程(2016)、首批国家一流本科课程(2020)及江苏省首批产教融合一流课程等;主持获省部级科研、教学二等奖2项;参与获国家教学成果2等奖1项、省级科技进步2等奖2项;获校级教学成果特等、1等、2等各1项。

参加学术团体及任职情况

国家肉羊产业技术体系岗位专家兼室主任;江苏省家畜胚胎工程研究中心主任、省肉羊产业技术体系首席专家、省肉羊育种协作组首席专家。中国畜牧兽医学会动物繁殖学分会副理事长、养羊学分会常务理事;中国农学会秸秆资源综合利用分会常务理事,全国草食动物健康生产科技创新联盟常务理事。第二届和第三届全国畜牧业标准化技术委员会委员,江苏省畜牧业标准化技术委员会委员。江苏省第三届畜禽资源委员会委员兼羊业分会主任委员。江苏省畜牧业协会常务理事、兼羊业分会副会长及秘书长。

承担科研项目

已主持完成国家重点研发计划项目、国家自然科学基金、省重点研发项目等40余项,目前主持国家自然科学基金面上项目2项、中埃国际合作基金1项。国家重点研发项目课题1项,并承担国家肉羊产业技术体系岗位科学家项目、江苏现代农业(肉羊)产业技术体系集成创新中心项目、江苏省农业重大新品种创制计划和中央重大技术协同推广项目等。

论文论著:

本人主要从事动物繁殖学和羊生产学教学、科研、人才培养和产教融合及推广工作,主要聚焦肉羊育种、胚胎工程、多胎与生长调控机制、饲料与营养及环境调控等。发表论文400多篇,其中SCI 文章200多篇,近几年发表的重要论文如下:

 

2023

Yixuan fan; zhen zhang; kaiping deng; ziqi kang; g, Jinjing Guoguomin zhang; yanli zhang; feng wang*CircUBE3A promotes myoblasts proliferation and differentiation by sponging miR-28-5p to enhance expressionInternational Journal of Biological Macromolecules 226 (2023) 730–745

Xiaodan Li, Xiaolei Yao, Yongjin Bao, Kaiping Deng, Mingtian Deng, Fan Yang, Xuan Sun, Peihua You, Qingxian Cai and Feng Wang*PPP2R2A promotes testosterone secretion in Hu sheep Leydig cells via activation of the AKT/mTOR signaling pathwayJournal of Molecular Endocrinology202370 (4): e220130

Kaiping DengZhipeng LiuYanlong SuZhen ZhangYixuan FanYanli ZhangFeng wang* Targeted Demethylation of the TGF beta 1 mRNA Promotes Myoblast Proliferation via Activating the SMAD2 Signaling PathwayCELLS2023127):

 

2022

Xiaoxiao Gao, Xiaodan Li, Zhibo Wang, Kang Li, Yaxu Liang, Xiaolei Yao, Guomin Zhang, Feng Wang*L-Argine regulates the proliferation, apoptosis and endocrine activity by alleviating oxidative stress in sheep endometrial epithelial cellsTheriogenology2022179187-196

Zhen Zhang;Yixuan Fan*;Kaiping Deng;Yaxu Liang;Guomin Zhang;Xiaoxiao GaoM. A.El-SamahyYanli ZhangMingtian DengFeng Wang*; Circular RNA circUSP13 sponges miR-29c to promote differentiation and inhibit apoptosis of goat myoblasts by targeting IGF1, Faseb JournalDOI: 10.1096/fj.202101317R

Mingtian DengBaobao Chen; Zifei Liu; Yongjie Wan; Dongxu Li; Yingnan Yang; Feng Wang*YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development. Cell & Bioscience (2022) 12:12https://doi.org/10.1186/s13578-022-00743-4

Xiaolei Yao, Fengzhe Li, Zongyou Wei, M A Ei-Samahy+埃及), Xu Feng, Fan Yang, Feng Wang*Integrative genome-wide DNA methylome and transcriptome analysis of ovaries from Hu sheep with high and low prolificFrontiers in Cell and Developmental Biology2022,(10):820558

Zhen ZhangKaiping DengZiqi KangFeng Wang*Yixuan Fan*MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13FASEB J. 2022;36:e22370. https://doi.org/10.1096/fj.202200246R

Xiaolei Yao,Mohamed AbdFatah El-Samahy,Xiaodan Li,Yongjin Bao,Jiahe Guo,Fan Yang,Zhibo Wang,Kang Li,Yanli Zhang,Feng Wang*LncRNA-412.25 activates the LIF/STAT3 signaling pathway in ovarian granulosa cells of Hu sheep by sponging miR-346. The FASEB Journal. 2022;36:e22467

Yixuan Fan#,Caifang Ren#,Kaiping Deng,Zhen Zhang,Juan Li,Mingtian Deng,Yanli Zhang, Feng Wang*The regulation of LncRNA GTL2 expression by DNA methylation During Sheep Skeletal Muscle DevelopmentGenomics, 2022,114 110453

 

2021

Mingtian Deng #, Yongjie Wan#, Zifei Liu1, Cai Yu1, Baobao Chen,  Yanli Zhang*, Feng Wang*, Long non-coding RNA lnc_3712 impedes nuclear  reprogramming via repressing Kdm5b,Molecular Therapy-Nucleic Acids,2021,24:54-66

Xiaolei Yao,XiaoXiao Gao, Yongjin Bao, Jinyu Yang, Xiaodan Li,  M.A.EI-Samahy,Zhibo Wang, Guomin Zhang, Yanli Zhang, Wujun Liu, Feng Wang*,LncRNA  FDNCR promotes apoptosis of granulosa cells by targeting the  miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep,Molecular  Therapy - Nucleic Acids,2021,24:223-240

Kaiping Deng,Yixuan Fan,Yaxu Liang,Yu Cai,Guomin Zhang,Mingtian  Deng,Zhibo  Wang,Jiawei Lu,Jianfe Shi,Haifeng Zhang,Yanli Zhang*,Feng  Wang*, FTO-mediated demethylation of GADD45B promotes myogenesis through the  activation of p38 MAPK pathway,Molecular Therapy - Nucleic Acids,2021,36:34-48

Li,Xiaodan; Yao,Xiaolei; Xie,Haiqiang; Gao,Xiaoxiao; Deng,Kaiping;  Bao,Yongjin; Feng,Wang*,SPATA6 promotes proliferation, testosterone production, and  inhibits apoptosis in Hu sheep Leydig cells,Theriogenology, 2021,166:9-20

Yu Cai#, Mingtian Deng#, Qifan Zhang, Zifei Liu, Liang Wang,  Wenwen Sheng, Yanli Zhang, Peihua You, Ziyu Wang*,Feng Wang*,Effects of dietary betaine  supplementation on biochemical parameters of blood and testicular oxidative  stress in Hu sheep,Theriogenology,2021,164:65-73

Xiaolei Yao,M.A. EI-Samahy,Shenhua Xiao,Zhibo Wang,Fanxing Meng,Xiaodan  Li,Yongjin Bao,Yanli Zhang,Ziyu Wang,Yixuan Fan,Feng Wang*, CITED4 mediates  proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in  vitro, Reproduction,2021,161:255-267

Mingtian Deng,Baobao Chen,Yingnan Yang,Yongjie Wan,Zifei Liu,Jun Fu,Feng Wang*Characterization of transcriptional activity during ZGA in mammalian SCNT embryoBiology of Reproduction20211054):905-917

Yaxu Liang,Zhen Zhang,Jiayu Tu,Zhibo Wang,Xiaoxiao Gao,Kaiping Deng,; M.A. El-Samahy, Peihua You, Yixuan Fan*,Feng Wang*,γ-Linolenic Acid Prevents Lipid Metabolism Disorder in Palmitic Acid-Treated Alpha Mouse Liver-12 Cells by Balancing Autophagy and Apoptosis via the LKB1-AMPK-mTOR Pathway, Journal of Agricultural and Food Chemistry20216929):8257-8267

2020

Zifei Liu#, Guomin Zhang#,Mingtian Deng,Hua Yang,Jing  Pang,Yu Cai,Yongjie Wan* and Feng Wang*,Inhibition of  lysine-specific histone demethylase 1A results in meiotic aberration during  oocyte maturation in vitro in goats,Theriogenology,2020,143:168-178

Mingtian Deng,Baobao Chen,Zifei  Liu,Yongjie Wan,Hua Yang,Yu Cai,Jianguo Zhou,Yanli Zhang,Feng Wang*,Aberrant DNA and histone methylation during zygotic genome  activation in goat cloned embryos,Theriogenology,2020,148:27-36

Yaxu Liang, Yongjin Bao, Xiaoxiao Gao, Kaiping Deng, Shiyu An,  Zhibo Wang, Xinai Huang, Dong Liu, Zhinan Liu, Feng Wang*,YX Fan*,Effects of spirulina supplementation on lipid metabolism disorder,  oxidative stress caused by high-energy dietary in Hu sheep,Meat Science,2020,164:108094 

Yixuan.Fan,Yaxu Liang,Kaiping Deng,Zhen Zhang,Guomin Zhang,Yanli  Zhang,Feng Wang*, Analysis of DNA Methylation Profiles during sheep Skeletal  Muscle Development Using Whole-genome Bisulfite Sequencing,BMC  genomics,2020,21:327 https://doi.org/10.1186/s12864-020-6751-5

Yu Cai,Mingtian Deng,Zifei Liu,Guomin Zhang,Jing  Pang,Shiyu An,Zhibo Wang,Yanli Zhang,Feng Wang*,EZH2  expression and its role in spermatogonial stem cell self-renewal in  goats.Theriogenology,2020,155:222-231 

Caifang Ren,Kaiping Deng,Zhibo Wang,Mingtian Deng,Yixuan  Fan,Yanli Zhang,Jianyu Ma, Shuting Wang,Zifei Liu,Feng Wang*,Reinterpreting  sheep muscle strand-specific RNA sequencing data showing extensive 3’UTR extensions,Animal  Genetics,2020,51:788-798。

Mingtian Deng,Guomin Zhang; Yu Cai; Zifei Liu; Yanli  Zhang; Fanxing Meng; Feng Wang; Yongjie Wan*,DNA  methylation dynamics during zygotic genome activation in goat,Theriogenology,2020,156:144-154

Xiaoxiao Gao, Xiaolei Yao, Zhibo Wang, Xiaohe Li, Xiaodan Li,  Shiyu An, Guo-Min Zhang, Feng Wang*,Long non-coding RNA366.2  controls endometrial epithelial cell proliferation and migration by  upregulating WNT6 as a ceRNA of miR-1576 in sheep uterus,JCP,BBA - Gene Regulatory Mechanisms,2020,1863:194606

Xiaolei Yao#;Zibo Wang#;Xiaoxiao Gao;Xiaodan Li;Hua  Yang;EI-Samahy M.A;Yongjin Bao; Shenhua Xiao;Fanxing Meng;Feng Wang*,Unconservative_15_2570409  suppress progesterone receptor expression in granulosa cells of Hu sheep,Theriogenology,2020,157:303-31

Guo-Min Zhang; Yi-Xuan Guo; Chun-Yu Cheng; El-Samahy M. A.; Ran  Tong; Xiao-Xiao Gao; Kai-Ping Deng; Feng Wang*; Zhi-hai Lei*,Arginine  infusion rescues ovarian follicular development in feed-restricted Hu sheep  during the luteal phase,Theriogenology,2020,158:75-83

Mingtian Deng, Baobao Chen, Yongjie Wan, Zifei Liu, Yu Cai,  Guoming Zhang, Yixuan Fan, YANLI ZHANG* and Feng Wang*,YTHDF2  regulates maternal transcriptome degradation and embryo development in goat,Frontiers in Cell and Developmental Biology,10.3389/fcell.2020.580367

2019

Yi-Xuan Guo#,Guo-Min Zhang#, Xiao-Lei Yao, Ran Tong,Chun-Yu  Cheng,Ting-Ting Zhang, Shu-Ting Wang,Hua Yang,Feng Wang*,Effects  of nitric oxide on steroidogenesis and apoptosis in goat luteinized granulosa  cells,Theriogenology,2019,126:55-62

Guo-Min Zhang,Ting-Ting Zhang,Shi-Yu An,M.A.El-Samahy,Hua  Yang,Yong-Jie Wan,Fan-Xing Meng,Shen-Hua Xiao,Feng Wang,Zhi-Hai Lei,Expression of  Hippo signaling pathway components in Hu sheep male reproductive tract and  spermatozoa, Theriogenology,2019,126:239-248

Guo-Min Zhang, Shi-Yu An, M. A. El-Samahy, Yan-Li Zhang,  Yong-Jie Wan,Zi-Yu Wang, Shen-Hua Xiao, Fan-Xing Meng, Feng Wang*, Zhi-Hai Lei*,Suppression of miR-1197-3p attenuates H2O2 induced apoptosis of  goat luteinized granulosa cells via targeting PPARGC1A,Theriogenology,2019,132:72-82

Kaiping Deng, Caifang Ren, Yixuan Fan, Jing Pang, Guomin Zhang,  Yanli Zhang, Pei-Hua You and Feng Wang*,YAP1 regulates PPARG and RXR  alpha expression to affect the proliferation and differentiation of ovine  preadipocyte,Journal of Cellular Biochemistry,2019;120:19578-19589

Yi xuan Fan,Caifang Ren,Guomin Zhang, Kaiping Deng,Fanxing  Meng,Feng wang*,Effects of  algae dietary supplementation on fatty acid composition and the expression of  genes involved in lipid metabolism in Hu sheep managed under intensive  finishing systems,Meat Science,2019,157:107872

Xiao-Xiao Gao, Qi-Fan Zhang, Ming Zhu, Xiao-He Li, Yi-Xuan Guo,  Jing Pang,Zi-Fei Liu, Pei-Hua You, Guo-Min Zhang, Feng Wang*,Effects of L-Arginine on endometrial estrogen receptor α/β and  progesterone receptor expression in nutrient-restricted Hu sheep,Theriogenology,2019,138:137-144

2018

Guo-Min Zhang,Ting-Ting Zhang, Yu-Hang Jin, Jian-Ling  Liu, Yi-Xuan Guo, Yi-Xuan Fan, M.A. El-Samahy. Fan-Xing Meng,Feng Wang*,  Zhi-Hai Lei*,Effect of caloric restriction and  subsequent re-alimentation on oxidative stress in the liver of Hu sheep ram  lambs,Animal Feed Science and Technology, 2018,237:68-77

Yi-Xuan Guo, Hai-Tao Nie, Chen-Jie Xu, Guo-Min Zhang, Ling-Wei  Sun,Ting-Ting Zhang, Zhen Wang, Xu Feng, Pei-Hua You, Feng Wang*,Effects  of nutrient restriction and arginine treatment on oxidative stress in the  ovarian tissue of ewes during the luteal phase,Theriogenology,2018,113:127-136

Xiaolei Yao,Mohmed El-samahy, Lijie Fan,Linfeng Zheng,Yuyue Jin,Jing pang,Guomin Zhang,Zifei Liu,Feng Wang*,In vitro influence of  Selenium on the proliferation of and steroidogenesis in goat luteinized  granulosa cells,Theriogenology,2018,114:70-80

Mingtian Deng, Zifei Liu, Caifang Ren, Guomin Zhang, Jing Pang,  Yanli Zhang, Feng Wang*,Yongjie Wan*, Long noncoding RNAs exchange  during zygotic genome activation in goat,Biology of  Reproduction,2018,99:707-717

Xiaoxiao Gao,Xiaohe Li,Qifan  Zhang,Ming Zhu,Yixuan Guo,Kaiping Deng,Guomin Zhang,Feng Wang*,Effects of L-arginine on  endometrial microvessel density in underfed Hu sheep,Theriogenology,2018,119:252-258

2017

Lingwei Sun; Yixuan Guo; Yixuan Fan; Haitao Nie; Ruocheng Wang;  Feng Wang*,Metabolic  profiling of stages of healthy pregnancy in Hu sheep using nuclear magnetic  resonance (NMR),Theriogenology,2017,92:121-128

Xiaolei Yao, Hua Yang, Yanli Zhang, Caifang Ren, Haitao Nie,  Yixuan Fan, Wenjun Zhou, Shuting Wang, Xu Feng, Feng Wang*,Characterization of  GALNTL5 gene sequence and expression in ovine testes and sperm,Theriogenology,2017,95:54-61

Yi-Xuan Guo, Hai-Tao Nie, Ling-Wei Sun , Guo-Min Zhang, Kai-Ping  Deng, Yi-Xuan Fan, Feng Wang*,Effects of diet and arginine treatment during the luteal  phase on ovarian NO/PGC-1a signaling in ewes,Theriogenology,2017,96:76-84

Yanli Zhang, Hua Yang, Le Han, Fengzhe Li, Tingting Zhang, Jing  Pang, Xu Feng,Caifang Ren,  Shengyong Mao, Feng Wang*,Long noncoding RNA expression profile changes associated with  dietary energy in the sheep testis during sexual maturation,Sci Rep.2017,12;7(1):5180-5192

Zhang, Yanli,Han, Le; Yang, Hua; Pang, Jing; Li, Peizhen; Zhang, Guomin;  Li, Fengzhe; Wang, Feng*, Bisphenol A affects cell viability involved in  autophagy and apoptosis in goat testis sertoli cell,Environmental Toxicology and Pharmacology,2017,55:137-147

Yanli Zhang,Fengzhe Li,Xu Feng,Hua Yang,Aoxiang Zhu,Jing Pang,Le Han,Tingting Zhang,Xiaolei Yao,Feng Wang *,Genome-wide Analysis of DNA Methylation Profiles on Sheep  ovaries Associated with Prolificacy Using Whole-genome Bisulfite Sequencing,BMC Genomics,2017 Oct 2;18(1):759. doi:  10.1186/s12864-017-4068-9

2016

Feifei Luo, Ruoxin Jia, Shijia Ying, Ziyu Wang, Feng Wang*。Analysis of Genes that  Influence Sheep Follicular Development by Different Nutrition Levels during  the Luteal Phase using Expression Profiling. Animal Genetics,2016,47:354-364

Hao Zhang, Lingwei Sun, Ziyu Wang, Mingtian Deng, Guoming  Zhang. Rihong Guo, Tiewei Ma, and Feng Wang*,Dietary N-carbamylglutamate  and Rumen-protected L-Arginine Supplementation ameliorate Fetal growth  restriction in undernourished ewes. Journal of Animal Science,2016,94:2072-2085

Rihong Guo#, Yongjie Wan#, Dan Xu, Libin Cui , Mingtian Deng ,  Guoming Zhang. Ruoxin Jia, Wenjun Zhou, Zhen Wang, Kaiping Deng, Mingrui  Huang, Feng Wang*, Yanli Zhang*,Generation and evaluation of Myostatin  Knock-out Rabbits and Goat Using CRISPR/Cas9 system, Scientific Reports,  2016, 6:29855

Hao Zhang, Lingwei Sun, Ziyu Wang, Mingtian Deng, Haitao Nie,  Guoming Zhang, Tiewei Ma and Feng Wang*. N-carbamylglutamate and L-arginine  improved maternal and placental development in underfed ewes, Reproduction,2016,151:623–635

Guomin Zhang; Mingtian Deng; Yanli Zhang; Yixuan Fan; Yongjie  Wan; Haitao Nie; Ziyu Wang; Feng Wang*; Zhihai Lei*. Effect of PGC-1α  overexpression or silencing on mitochondrial apoptosis of goat luteinized  granulosa cells. Journal of Bioenergetics and Biomembranes,2016,48:493-507

 

出版教材、著作30多部,其中主编、副主编如下:

1.主编《动物繁殖学》(第二版),中国农业大学出版社,2022.06,北京

2.第一主编《动物繁殖学实验教程》(第二版),中国农业大学出版社,2017.07,北京

3.第一主编《牛羊繁殖学》,中国农业出版社,2003.12,北京

4.主编《羊业科学研究进展(2015)》,中国农业科学技术出版社, 2015.10,北京

5.第二主编《肉用山羊养殖与疫病防治新技术》,中国农业科学技术出版社, 2015.12,北京

6.第三主编《肉羊标准化高效养殖关键技术》,江苏凤凰科技出版社,2016,10,南京

7.主编《高产奶牛养殖7日通》,中国农业出版社,2004.01,北京

8.主编《高产奶牛绿色养殖新技术》,中国农业出版社,2003.07,北京

9.主编《肉牛绿色养殖新技术》,中国农业出版社,2003.05,北京

10.主编《无公害牛奶生产技术》,云南科技出版社,2002.12,昆明

11.主编《肉羊饲养新技术》,中国农业科学技术出版社,2013.04,北京

12.副主编《动物繁殖技术》,中国农业出版社,2010.06,北京

 

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