李向飞

性 别

男

学历学位

农学博士

职 称

副教授

导师类别

博士生导师

专业领域

水产动物营养与饲料

研究方向

水产动物营养与代谢调控；功能性饲料添加剂研发；新型饲料资源开发

教育与工作经历

2013年9月至今，南京农业大学动物科技学院任教；

2018年12月至2019年12月，美国普渡大学农学院访问学者；

2008年9月-2013年6月，南京农业大学，南京农业大学动物营养与饲料科学专业攻读博士；

2004年9月-2008年6月，河南工业大学，动物科学专业攻读本科。

联系方式

xfli@njau.edu.cn；025-84395382

奖励及荣誉

1、 南京农业大学“钟山学者计划”学术新秀；

2、 南京农业大学动物科技学院青年教师授课比赛一等奖； 

3、南京农业大学动物科技学院“丰泽农牧奖教金”；

4、神农中华农业科技奖二等奖，获奖成果名称：团头鲂绿色养殖全程关键技术体系创制与应用，排名第七；

5、神农中华农业科技奖三等奖，获奖项目名称：异育银鲫绿色功能性饲料研发与推广，排名第八；

6、第四届江苏省海洋与渔业科技创新奖一等奖，获奖项目名称：绿色水产营养调控技术体系构建及其在淡水鱼虾中的应用，排名第十；

7、中国水产科学研究院科技进步奖一等奖，获奖成果名称：团头鲂养殖全过程营养需要和健康高效饲料研发与示范推广，排名第八； 

参加学术团体及任职情况

担任Animals编委，Animal Nutrition英文责编，及EBioMedicine、Science of the Total Environment、British Journal of Nutrition、Aquaculture、Genome、Reviews in Aquaculture、Amino Acids、Comparative Biochemistry and Physiology、Frontiers in Physiology、Aquaculture Nutrition、Journal of the Science of Food and Agriculture、Fish Physiology and Biochemistry、Aquaculture Research、Journal of the World Aquaculture Society、水产学报、中国水产科学、水生生物学报等期刊审稿人。

承担科研项目

1、国家自然科学基金面上项目---“基于mMg²⁺稳态研究高糖致鱼体线粒体功能障碍机制”；

2、国家自然科学基金面上项目---“转录辅激活因子PGC1β介导的高糖诱导团头鲂线粒体功能损伤机制研究”；

3、国家自然科学基金青年基金项目---“RNA结合蛋白QKI调控团头鲂糖异生作用的分子机制研究”；

4、江苏省自然科学基金面上项目---“ULK1调控PINK1/Parkin介导高糖抑制团头鲂线粒体自噬机制研究”；

5、江苏省自然科学基金青年基金项目---“高糖胁迫下团头鲂AMPK通路磷酸化水平分析及二甲双胍对其的调控研究”；

6、江苏省农业科技自主创新资金项目---“鱼类肝胆综合症靶向胆汁酸产品创制”；

7、中央高校基本科研业务费专项资金项目---“RNA结合蛋白QKI介导的团头鲂胰岛素敏感性调控机制研究”；

8、大北农青年学者提升专项基金项目---“基于氨基酸感知的棉粕酶解蛋白调控中华绒螯蟹生长机制研究”。

论文论著：

一、论文

1. Zhang Ling, Ge Ya-Ping, Huang Yang-Yang, Chen Wei-Liang, Liu Wen-Bin, Zhang Ding-Dong, Li Xiang-Fei*. Benfotiamine attenuates the high-carbohydrate diet-induced mitochondrial redox imbalance in fish Megalobrama amblycephala by activating SIRT3 [J]. Aquaculture, 2023, 572: 739553.

2. Zhang Ling, Liu Zi-Shang, Deng Ying, He Chao-Fan, Liu Wen-Bin, Li Xiang-Fei*. The benefits of nanosized magnesium oxide in fish Megalobrama amblycephala: Evidence in growth performance, redox defense, glucose metabolism, and magnesium homeostasis [J]. Antioxidants, 2023, 12: 1350.

3. Liu Ming-Yang, Sun Miao, Zhang Ling, Ge Ya-Ping, Liu Bo, Li Xiang-Fei*. The essentiality of dietary myo-inositol to oriental river prawn (Macrobrachium nipponense): Evidence in growth performance, lipid metabolism and mitochondrial function [J]. Aquaculture, 2023, 567: 739304.

4. Ge Ya-Ping, Zhang Ling, Chen Wei-Liang, Sun Miao, Liu Wen-Bin, Li Xiang-Fei*. Resveratrol modulates the redox response and bile acid metabolism to maintain the cholesterol homeostasis in fish Megalobrama amblycephala offered a high-carbohydrate diet [J]. Antioxidants, 2023, 12: 121.

5. Chen Wei-Liang, Ge Ya-Ping, Sun Miao, He Chao-Fan, Zhang Ling, Liu Wen-Bin, Li Hong-Xia, Li Xiang-Fei*. Insights into the correlations between prebiotics and carbohydrate metabolism in fish: Administration of xylooligosaccharides in Megalobrama amblycephala offered a carbohydrate-enriched diet [J]. Aquaculture, 2022, 561: 738684.

6. Ge Ya-Ping, Chen Wei-Liang, Sun Miao, Zhang Ling, Liu Wen-Bin, Li Xiang-Fei*. Molecular characterization of farnesoid X receptor alpha in Megalobrama amblycephala and its potential roles in high-carbohydrate diet-induced alterations of bile acid metabolism [J]. Journal of Steroid Biochemistry and Molecular Biology, 2022, 219: 106065.

7. Jean-Jacques Yao Adjoumani, Kenneth Prudence Abasubong, Zhang Ling, Ge Ya-Ping, Liu Wen-Bin, Li Xiang-Fei*. A time-course study of the effects of a high-carbohydrate diet on the growth performance, glycolipid metabolism and mitochondrial biogenesis and function of blunt snout bream (Megalobrama amblycephala) [J]. Aquaculture, 2022, 552: 738011.

8. Xu Chao, Li Yuan-You, Paul B. Brown, Liu Wen-Bin, Gao Liu-Ling, Ding Zhi-Rong, Li Xiang-Fei *, Xie Di-Zhi *. Interactions between dietary carbohydrate and thiamine: Implications on the growth performance and intestinal mitochondrial biogenesis and function of Megalobrama amblycephala [J]. British Journal of Nutrition, 2022, 127: 321-334.

9. Zhang Ling, Zheng Xiao-Chuan, Huang Yang-Yang, Ge Ya-Ping, Sun Miao, Chen Wei-Liang, Liu Wen-Bin, Li Xiang-Fei*. Carbonyl cyanide 3-chlorophenylhydrazone induced the imbalance of mitochondrial homeostasis in the liver of Megalobrama amblycephala: A dynamic study [J]. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2021, 244: 109003.

10. Zhang Li, Liu Wen-Bin, Paul B. Brown, Xu Chao, Shi Hua-Juan, Zheng Xiao-Chuan, Zhang Ling, Huang Yang-Yang, He Chang, Li Xiang-Fei*. Utilization of raw and gelatinized starch by blunt snout bream Megalobrama amblycephala as evidenced by the glycolipid metabolism, glucose tolerance and mitochondrial function [J]. Aquaculture, 2020, 529: 735603.

11. Shi Hua-Juan, Liu Wen-Bin, Xu Chao, Zhang Li, Liu Jie, Zhang Ding-Dong, Zhang Ling, Li Xiang-Fei*. Transcriptional regulation of the AMP-activated protein kinase and glycolipid metabolism-related genes by insulin and glucagon in blunt snout bream (Megalobrama amblycephala): A comparative study [J]. Aquaculture, 2020, 515: 734553.

12. Li Xiang-Fei, Wang Bing-Ke, Xu Chao, Shi Hua-Juan, Zhang Li, Liu Jia-Dai, Tian Hong-Yan, Liu Wen-Bin. Regulation of mitochondrial biosynthesis and function by dietary carbohydrate levels and lipid sources in juvenile blunt snout bream Megalobrama amblycephala [J]. Comparative Biochemistry and Physiology Part A, 2019, 227: 14-24.

13. Abasubong Kenneth Prudence, Liu Wen-Bin, Adjoumani Yao Jean-Jacques, Xia Si-Lei, Xu Chao, Li Xiang-Fei*. Xylooligosaccharides benefits the growth, digestive functions and TOR signaling in Megalobrama amblycephala fed diets with fish meal replaced by rice protein concentrate [J]. Aquaculture, 2019, 500: 417-428.

14. Xu Chao, Liu Wen-Bin, Remø Sofie Charlotte, Wang Bing-Ke, Shi Hua-Juan, Zhang Li, Liu Jia-Dai, Li Xiang-Fei*. Feeding restriction alleviates high carbohydrate diet-induced oxidative stress and inflammation of Megalobrama amblycephala by activating the AMPK-SIRT1 pathway [J]. Fish & Shellfish Immunology, 2019, 92: 637-648.

15. Xu Chao, Liu Wen-Bin, Zhang Ding-Dong, Cao Xiu-Fei, Shi Hua-Juan, Li Xiang-Fei*. Interactions between dietary carbohydrate and metformin: Implications on energy sensing, insulin signaling pathway, glycolipid metabolism and glucose tolerance in blunt snout bream Megalobrama amblycephala [J]. Aquaculture, 2018, 483: 183-195.

16. Xu Chao, Liu Wen-Bin, Zhang Ding-Dong, Shi Hua-Juan, Zhang Li, Li Xiang-Fei*. Benfotiamine, a lipid-soluble analogue of vitamin B1, improves the mitochondrial biogenesis and function of blunt snout bream (Megalobrama amblycephala) fed high-carbohydrate diets by promoting the AMPK/PGC-1β/NRF-1 axis [J]. Frontiers in Physiology, 2018, 9: 1079.

17. Shi Hua-Juan, Xu Chao, Liu Ming-Yang, Wang Bing-Ke, Liu Wen-Bin, Chen Dan-Hong, Zhang Li, Xu Chen-Yuan, Li Xiang-Fei*. Resveratrol improves the energy sensing and glycolipid metabolism of blunt snout bream Megalobrama amblycephala fed high-carbohydrate diets by activating the AMPK–SIRT1–PGC-1α network [J]. Frontiers in Physiology, 2018, 9: 1258.

18. Xu Chao, Liu Wen-Bin, Dai Yong-Jun, Jiang Guang-Zhen, Wang Bing-Ke, Li Xiang-Fei*. Long-term administration of benfotiamine benefits the glucose homeostasis of juvenile blunt snout bream Megalobrama amblycephala fed a high-carbohydrate diet [J]. Aquaculture, 2017, 470: 74-83.

19. Xu Chao, Liu Wen-Bin, Zhang Ding-Dong, Wang Kai-Zhou, Xia Si-Lei, Li Xiang-Fei*. Molecular characterization of AMP-activated protein kinase α2 from herbivorous fish Megalobrama amblycephala and responsiveness to glucose loading and dietary carbohydrate levels [J]. Comparative Biochemistry and Physiology Part A, 2017, 208: 24-34.

20. Wang Bing-Ke, Liu Wen-Bin, Xu Chao, Cao Xiu-Fei, Zhong Xiao-Qun, Shi Hua-Juan, Li Xiang-Fei*. Dietary carbohydrate levels and lipid sources modulate the growth performance, fatty acid profiles and intermediary metabolism of blunt snout bream Megalobrama amblycephala in an interactive pattern [J]. Aquaculture, 2017, 481: 140-153.

21. Li Xiang-Fei, Xu Chao, Zhang Ding-Dong, Jiang Guang-Zhen, Liu Wen-Bin. Molecular characterization and expression analysis of glucokinase from herbivorous fish Megalobrama amblycephala subjected to a glucose load after the adaption to dietary carbohydrate levels [J]. Aquaculture, 2016, 459:89-98.

22. Li Xiang-Fei, Wang Fei, Qian Yu, Jiang Guang-Zhen, Zhang Ding-Dong, Liu Wen-Bin. Dietary vitamin B12 requirement of fingerling blunt snout bream Megalobrama amblycephala determined by growth performance, digestive and absorptive capability and status of the GH-IGF-I axis [J]. Aquaculture, 2016, 464: 647-653.

23. Li Xiang-Fei, Jiang Guan-Zhen, Qian Yu, Xu Wei-Na, Liu Wen-Bin. Molecular characterization of lipoprotein lipase from blunt snout bream Megalobrama amblycephala and the regulation of its activities and expression by dietary lipid levels [J]. Aquaculture, 2013, 416-417: 23-32.

24. Li Xiang-Fei, Jiang Yang-Yang, Liu Wen-Bin, Ge Xian-Ping. Protein-sparing effect of dietary lipid in practical diets for blunt snout bream (Megalobrama amblycephala) fingerlings: effects on digestive and metabolic responses [J]. Fish Physiology and Biochemistry, 2012, 38(2): 529-541

25. Li Xiang-Fei, Liu Wen-Bin, Jiang Yang-Yang, Zhu Hao, Ge Xian-Ping. Effects of dietary protein and lipid levels in practical diets on growth performance and body composition of blunt snout bream (Megalobrama amblycephala) fingerlings [J]. Aquaculture, 2010, 303(1): 65-70.

二、专利

1. 李向飞，徐超，刘文斌，张定东，蒋广震. 一种水产糖代谢调控组合物及其制备方法与应用[P]. 中国专利，2021年12月，专利号：ZL201811316474.1；

2. 李向飞，刘文斌，徐超，蒋广震，张定东. 一种改善鱼体糖耐受性的调控组合物及其制备方法与应用[P]. 中国专利，2019年2月，专利号：ZL201510811938.6;

3. 李向飞，刘文斌，王冰柯，蒋广震，张定东. 一种渔用糖代谢调控物及其制备方法与应用[P]. 中国专利，2018年9月，专利号：ZL201610261110.2;

4. 李向飞，张玲，刘文斌，何超凡，张定东，蒋广震，迟骋，刘恒彤. 一种青虾零售短期维生装置[P]. 中国专利，2022年7月，专利号：ZL202220922828.2；

5. 刘文斌，李向飞，徐维娜，蒋广震. 一种蛋白节约型团头鲂幼鱼配合饲料及其制备方法[P]. 中国专利，2013年10月，专利号：ZL201210558716.4。