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教师目录

刘军花

来源: 发布时间 : 2021-06-10 点击量:

   

刘军花

   

学历学位

研究生学历、农学博士学位

   

副教授

导师类别

硕士生导师

专业领域

动物营养与饲料科学

研究方向

反刍动物消化道营养;犊牛/羔羊胃肠道发育与营养调控

教育与工作经历

200309-200706月,东北农业大学,动物科学专业攻读本科

200709-200912月,南京农业大学,动物营养与饲料科学专业攻读硕士

201109-201406月,南京农业大学,动物营养与饲料科学专业攻读博士

201002-201108月,在南京农业大学任科研助理

201409月至今,在南京农业大学动物科技学院任教

联系方式

liujunhua@njau.edu.cn025-84395523

奖励及荣誉

2014年,南京农业大学优秀毕业生;2015年,江苏省优秀博士学位论文;2016年,动科院青年教师科研汇报一等奖;2017年,全国百名优秀博士后基金获得者选介;2018年,南京农业大学钟山学术新秀;2019年,教育部自然科学奖二等奖(排名第三)

参加学术团体及任职情况

刘军花,博士,副教授,江西省新干县人,2007年本科毕业于东北农业大学动物科学专业,之后在南京农业大学动物营养与饲料科学专业获得硕士和博士学位,20149月至今在南京农业大学动物科技学院消化道微生物实验室从事教学科研工作,其中20177月至10月在澳大利亚西澳大学合作研究,20183月至20193月在加拿大阿尔伯塔大学访学;承担动物营养学、饲料学、反刍动物营养及消化道微生物等本科生和研究生课程;美国动物科学协会会员(ASAS)、中国畜牧兽医学会动物营养学分会会员。Journal of Dairy ScienceJournal  of Animal ScienceAnimalSmall  Ruminant ResearchJournal of  Agricultural and Food ChemistryFrontiers in  Microbiology等杂志审稿人。

承担科研项目

1.  中央高校基本科研业务费,新疆塔里木马鹿高效利用荒漠粗饲料的瘤胃微生物及上皮生理响应机制,5万元,2021.01-2021.12,在研,主持;2.国家重点研发计划子任务,2018YFD0501906,东部地区山羊高效安全养殖技术集成与示范推广,2018.6-2021.0640万元,结题,课题骨干;3.中央高校基本科研业务费,早期断奶损伤羔羊小肠上皮屏障功能的机制与营养干预研究,2018.01-2018.1210万元,结题,主持; 4.国家自然科学基金青年基金,31501980,基于GLP-2信号通路研究高直链淀粉日粮促进羔羊小肠上皮生长的分子机制,2016/01-2018/1224万元,结题,主持;5.江苏省自然科学基金青年基金,BK20150655,高直链淀粉日粮对羔羊小肠上皮细胞周期的调节及内分泌机理研究,2015/07-2018/0620万元,结题,主持;6.中国博士后基金特别资助,2016T90474,甜味剂通过GLP-2促进羔羊小肠上皮紧密连接形成的机制,2016/07-2017/0715万元,结题,主持;7.中国博士后基金面上项目,2015M570462GLP-2促进羔羊小肠上皮细胞增殖的分子机制研究,2015/07-2017/068万元,结题,主持;8.江苏省博士后科研资助计划,TLR/NF-κB信号通路在SARA引发的瘤胃炎症中的作用机制研究,2014/09-2016/061.5万元,结题,主持;9.中央高校基本科研业务费,KJQN201610,基于GLP-2信号通路研究高直链淀粉日粮促进羔羊小肠上皮生长的分子机制,2016/01-2018/1210万元,结题,主持;10.奶牛营养学北京市重点实验室开放课题,kf2016043,基于宏基因组学研究SARA对奶牛瘤胃和后肠菌群结构与功能的影响,2016.05-2017.1210万元,结题,主持;11.国家重点研发项目子课题(2016YFD0501206),羊妊娠毒血症的发病机制及营养防控技术研究,2016/07-2020/1268万元,结题,参与(2/7)

论文论著:

1.        Sun DM, Yin YY, Guo CZ , Liu LX, Mao SY, Zhu WY, Liu JH*(通讯作者). Transcriptomic analysis reveals the molecular mechanisms of rumen  wall morphological and functional development induced by different solid diet  introduction in a lamb model. Journal of Animal Science and Biotechnology, 2021,  12:33.

2.        Sun DM, Mao SY, Zhu WY, Liu JH*(通讯作者). Effects of starter feeding on caecal mucosal bacterial  composition and expression of genes involved in immune and tight junctions in  preweaned twin lambs. Anaerobe, 2019, 59:167-175.

3.        Sun DM1, Liu LX1, Mao SY, Zhu WY, Liu  JH*(通讯作者). Aspartame supplementation in starter accelerates small  intestinal epithelial cell cycle and stimulates secretion of glucagon-like  peptide-2 in pre-weaned lambs. Journal of Animal Physiology and Animal  Nutrition, 2019,  103(5):1338–1350

4.        Liu JH, Li HW, Zhu WY, Mao SY*.  Dynamic changes in rumen fermentation and bacterial community following rumen  fluid transplantation in a sheep model of rumen acidosis: implications for  rumen health in ruminants. The FASEB Journal, 2019, 33(7): 8453–8467.

5.        Zhang RY1, Liu YJ1, Yin YY, Jin W, Mao SY,  Liu JH*(通讯作者). Response of rumen microbiota, and  metabolic profiles of rumen fluid, liver and serum of goats to high-grain  diets. Animal, 2019, 13(9):1855-1864.

6.        Liu LX, Sun DM, Mao SY, Zhu WY, Liu JH*(通讯作者). Infusion  of sodium butyrate promotes rumen papillae growth and enhances expression of  genes related to rumen epithelial VFA uptake and metabolism in neonatal  twin lambs. Journal of Animal Science, 2019, 97(2): 909-921.

7.        Liu JH, Xue CX, Sun DM, Zhu WY, Mao SY*. Impact of high-grain diet feeding  on mucosa-associated bacterial community and gene expression of tight  junction proteins in the small intestine of goats. MicrobiologyOpen,  2019, 8(6): e00745.

8.        Sun DM, Mao SY, Zhu WY, Liu JH*(通讯作者). Effect of starter diet supplementation on rumen epithelial  morphology and expression of genes involved in cell proliferation and metabolism  in pre-weaned lambs. Animal.  2018, 12(11): 2274-2283.

9.        Sun DM, Li HW, Mao SY, Zhu WY, Liu JH*(通讯作者). Effects of different starch source of starter on small  intestinal growth and endogenous GLP-2 secretion in pre-weaned lambs. Journal  of Animal Science. 2018, 96(1): 306-317.

10.     Liu JH, Bian GR, Sun DM, Zhu WY,  Mao SY*. Starter feeding supplementation alters colonic mucosal bacterial  communities and modulates mucosal immune homeostasis in newborn lambs.  Frontiers in Microbiology. 2017, 8: 429.

11.     Liu JH, Bian GR, Sun DM, Zhu WY,  Mao SY*. Starter feeding altered ruminal epithelial bacterial communities and  some key immune-related genes expression before weaning in lambs. Journal of  Animal Science. 2017, 95(2): 910-921.

12.     Liu JH, Zhang ML, Xue CX, Zhu WY,  Mao SY*. Characterization and comparison of the temporal dynamics of ruminal  bacterial microbiota colonizing rice straw and alfalfa hay within ruminants.  Journal of Dairy Science. 2016, 99 (12): 9668-9681.

13.     Liu JH, Zhang ML, Zhang RY, Zhu  WY, Mao SY*. Comparative  studies of the composition of bacterial microbiota associated with the  ruminal content, ruminal epithelium and in the faeces of lactating dairy  cows. Microbial biotechnology. 2016, 9(2): 257-268.

14.     Ye HM1, Liu JH1 (共同一作), Feng PF, Zhu WY, Mao SY*. Grain-rich diets altered the colonic  fermentation and mucosa-associated bacterial communities and induced mucosal injuries  in goats. Scientific reports. 2016, 6.

15.     Liu JH, Bian GR, Zhu WY, Mao SY*. High-grain feeding causes strong  shifts in ruminal epithelial bacterial community and expression of Toll-like  receptor genes in goats. Frontiers in Microbiology. 2015, 6: 167.

16.     Liu JH, Xu TT, Zhu WY, Mao SY*.  High-grain feeding alters caecal bacterial microbiota composition and  fermentation and results in caecal mucosal injury in goats. British Journal  of Nutrition. 2014, 112(3): 416-427.

17.     Liu JH, Xu TT, Zhu WY, Mao SY*. A  high-grain diet alters the omasal epithelial structure and expression of  tight junction proteins in a goat model. The Veterinary Journal. 2014,  201(1): 95-100.

18.     Liu JH, Xu TT, Liu YJ, Zhu WY, Mao  SY*. A High-grain diet causes massive disruption of ruminal epithelial tight  junctions in goats. American Journal of Physiology-Regulatory, Integrative  and Comparative Physiology. 2013, 305(3): R232-241.

19.     Lin LM, Wang Y, Xu L, Liu JH, Zhu WY, Mao SY*.  Microbiome–host co-oscillation patterns in remodeling of colonic homeostasis  during adaptation to a high-grain diet in a sheep model. Animal Microbiome,  2020, 2(1).

20.     Zhang RY, Liu JH, Jiang LS, Mao SY*.  Effect of  high-concentrate diets on microbial composition, function, and the VFAs  formation process in the rumen of dairy cows. Animal Feed Science and  Technology, 2020, 269: 114619.

21.     Guo CZ, Xue YF, Yin YY, Sun DM, Xuan HP, Liu JH, Mao SY*.  The effect of glycerol or rumen-protected choline chloride on rumen  fermentation and blood metabolome in pregnant ewes suffering from negative  energy balance. Animal Feed Science and Technology, 2020, 268: 114594

22.     Ehab BT, Hossam ES, Xie F, Wang XF, Liu JH, Mao SY*.  Effect of pelleted high-grain total mixed ration on rumen morphology,  epithelium-associated microbiota and gene expression of proinflammatory  cytokines and tight junction proteins in Hu sheep. Animal Feed Science and  Technology, 2020, 263: 114453

23.     Lin LM1, Xie F1, Sun DM, Liu JH,  Zhu WY, Mao SY*. Ruminal microbiome-host crosstalk stimulates the development  of the ruminal epithelium in a lamb model. 2019, 7(1): 1-16.

24.     Xue Y, Guo C, Hu F, Liu JH, Mao SY*. Hepatic Metabolic  Profile Reveals the Adaptive Mechanisms of Ewes to Severe Undernutrition  during Late Gestation . Metabolites, 2018

25.    Hu F, Xue YF, Guo CZ, Liu JH, Mao SY*.  The response of ruminal fermentation, epithelium-associated microbiota, and  epithelial barrier function to severe feed restriction in pregnant ewes.  Journal of Animal Science, 2018, 96(10): 4293-4305.

26.    Xu L,  Wang Y, Liu JH, Zhu WY, Mao SY*.  Morphological adaptation of sheep’s rumen epithelium to high-grain diet  entails alteration in the expression of genes involved in cell cycle  regulation, cell proliferation and apoptosis. Journal of Animal Science and Biotechnology,  2018, 9(1): 32.

27.    Zhang  RY, Jin W, Feng PF, Liu JH, Mao SY*.  High-grain diet feeding altered the composition and functions of the rumen  bacterial community and caused the damage to the laminar tissues of goats.  Animal, 2018: 1-10.

28.    Guo  CZ, Li HW, Sun DM, Liu JH, Mao SY*.  Effects of abomasal supplementation of quercetin on performance, inflammatory  cytokines, and matrix metalloproteinase genes expression in goats fed a  high-grain diet. Livestock Science, 2018, 209: 20-24.

29.    Li  HW, Liu JH, Zhu WY, Mao SY*.  Intraruminal infusion of oligofructose alters ruminal microbiota and induces  acute laminitis in sheep. Journal of Animal Science. 2017, 95(12), 5407-5419.

30.    Wang  Y, Xu L, Liu JH, Zhu WY, Mao SY*. A  High Grain Diet Dynamically Shifted the Composition of Mucosa-Associated  Microbiota and Induced Mucosal Injuries in the Colon of Sheep. Frontiers in  Microbiology. 2017, 8.

31.    Zhang  RY, Ye HM, Liu JH, Mao SY*.  High-grain diets altered rumen fermentation and epithelial bacterial  community and resulted in rumen epithelial injuries of goats. Applied Microbiology  and Biotechnology. 2017, 101(18): 6981-6992.

32.    Jin  W, Xue CX, Liu JH, Yin YY, Zhu WY, Mao SY*.  Effects of Disodium Fumarate on In Vitro Rumen Fermentation, the Production  of Lipopolysaccharide and Biogenic Amines, and the Rumen Bacterial Community.  Current Microbiology. 2017, 74(11), 1337-1342.

33.    Wang  Y, Liu JH, Yin YY, Zhu WY, Mao SY*.  Rumen microbial and fermentation characteristics are affected differently by  acarbose addition during two nutritional types of simulated severe subacute  ruminal acidosis in vitro. Anaerobe. 2017, 47, 39-46.

34.    Mao  SY*, Huo WJ, Liu JH, Zhang RY, Zhu  WY. In vitro effects of sodium bicarbonate buffer on rumen fermentation,  levels of lipopolysaccharide and biogenic amine, and composition of rumen  microbiota. Journal of the Science of Food and Agriculture. 2017, 97: 1276-1285.

35.    Zhang  RY, Liu JH, Mao SY*. Impact of  Subacute Ruminal Acidosis (SARA) on Ruminal Microbiome, Lipopolysaccharide  and Bioamine and Rumen Epithelial Health of Dairy Cows. 2017, Dairy and Vet  Sci J. 2017; 1(2): 555556.DOI: 10.19080/JDVS.2017.01.555556.

36.    Bian  GR, Ma SQ, Zhu ZG, Su Y, Zoetendal EG, Mackie R, Liu JH, Mu CL, Huang  RH, Smidt H, Zhu WY*. Age, Introduction of  Solid Feed and Weaning Are More Important Determinants of Gut Bacterial  Succession in Piglets Than Breed and Nursing Mother as Revealed by a  Reciprocal Cross-Fostering Model. Environmental Microbiology. 2016, 18 (5):  1566-1577.

37.    Mao SY*, Zhang ML, Liu JH, Zhu WY. Characterising the bacterial  microbiota across the gastrointestinal tracts of dairy cattle: membership and  potential function. Scientific reports. 2015, 5.

38.     Wang XF, Mao SY, Liu JH, Zhang LL, Cheng YF, Jin W, Zhu  WY*. Effect of the gynosaponin on methane production and microbe  numbers in a fungus-methanogen co-culture. Journal  of Animal and Feed Sciences. 2011, 20: 272–284.

39.     孙大明1,殷雨洋1,吴建良,刘理想,毛胜勇,刘军花*(通讯作者). 早期补饲粉状精料和颗粒料对羔羊生长性能及胃肠道发育的影响. 草业学报,202029(7): 184-192.

40.     王璐,刘理想,孙大明,刘军花*(通讯作者).丁酸调控幼龄反刍动物瘤胃上皮发育研究进展. 生物技术通报, 2020, 36(2): 49-57

41.     刘理想, 孙大明, 毛胜勇, 刘军花*(通讯作者). 胰高血糖素样肽-2对羔羊胃肠道重量, 瘤胃发酵及小肠上皮发育相关基因表达的影响. 畜牧兽医学报, 201849(3):  549-558.

42.     孙大明,李弘伟,毛胜勇,刘军花*(通讯作者). 断奶前补饲不同直"支链淀粉比开食料对羔羊瘤胃上皮发育的影响. 草业学报, 201827(8):  118-125.

43.     孙大明,毛胜勇,刘军花*(通讯作者). 长期高谷物饲喂对山羊瘤胃酸中毒发生的影响. 畜牧兽医学报. 2016, 47(12): 2420-2429.

44.      刘军花,朱伟云,毛胜勇*. 高谷物日粮促进山羊瘤胃上皮单羧酸转运蛋白1及钠钾ATPmRNA的表达. 草业学报. 2017, 26 (2):  95-101.

45.     李弘伟,刘军花,霍文捷,朱伟云,毛胜勇*. 高精料日粮对山羊瘤胃和盲肠发酵及生物胺生成及吸收的影响研究,草业学报.  2017, 26(6): 210-216

46.     金巍, 刘军花, 李袁飞, 成艳芬, 朱伟云*. 甲烷菌对厌氧真菌不同碳源代谢的影响. 微生物学 . 2017, 57(5): 1-6

47.     王晓成,刘军花,朱伟云,毛胜勇*.瘤胃源酵母的分离筛选及对不同底物发酵能力影响.草业学报. 2016, 25(5): 141-148.

48.     薛春旭,叶慧敏,冯泮飞,刘军花,毛胜勇*.高谷物日粮对山羊小肠发酵、肠道结构和微生物菌群数量的影响研究.草业学报. 2016, 25(5): 175-183.

49.     冯泮飞,刘军花,叶慧敏,朱伟云,毛胜勇*. 寡果糖诱导瘤胃急性酸中毒对山羊瘤胃发酵、蹄组织结构及炎症因子、金属蛋白酶表达的影响,动物营养学报,2016, 28(7): 2260-2268.

50.     郭长征,冯泮飞,薛春旭,叶慧敏,刘军花,毛胜勇*. 高精料饲粮添加槲皮素对山羊瘤胃发酵、瘤胃菌群数量及血清指标的影响. 动物营养学报. 2016, 28(9): 2839-2846.

51.     刘玉洁, 刘军花, 许婷婷, 毛胜勇*. 谷氨酰胺对饲喂高精料奶山羊盲肠黏膜形态及炎症因子mRNA表达的影响. 动物营养学报. 2014, 26(2):  513-518.

52.     刘玉洁,刘军花,许婷婷,毛胜勇*. 谷氨酰胺对饲喂高精料的奶山羊瘤胃上皮的保护效应研究。草业学报.  2014, 23(4): 293-299.

 

授权发明专利:

        阿斯巴甜在动物饲料中作为添加剂在预防幼龄反刍动物断奶应激腹泻中的应用;2020011500627430, 刘军花、毛胜勇、朱伟云、孙大明、刘理想

 

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