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姓  名:
朱伟云
性  别:
职  称:
教授、博士生导师
最高学历:
博士
毕业院校:
英国阿伯丁大学
专业领域:
消化道微生物及其对动物生长和保健作用
联系方式:
E-mail:zhuweiyun@njau.edu.cn Tel:025-84395523
研究方向:
消化道微生物及其对动物生长和保健作用
参加学术团体及任职情况:
南京农业大学动物科技学院消化道微生物研究室主任
承担项目:
(1)国家自然科学基金项目:瘤胃纤维降解产甲烷过程中厌氧真菌与甲烷菌代  谢关系机制及其作用,(31072052),2011.1-2013.12。  
(2)国家公益性行业(农业)科研专项:气候变化对农业生产的影响及应对技术研究(项目编号:200903003),主持课题“气候变化对畜牧生产的影响”,2009.12-2012.12。  
(3) 国际合作项目(中国科技部——澳大利亚创新工业科技部):未培养瘤胃甲烷菌的宏基因组学分析研究。(2010DFA31040), 2010年7月1日 - 2013年6月30日 ,参加。  
(4) 欧盟第7框架项目(FP7-KBBE-2008-2B),INTERPLAY  Interplay of microbiota and gut function in the developing pig  Innovative avenues towards sustainable animal production。2009年1月-2012年12月,partner,中方主持。  
(5)国家自然科学基金重大国际合作项目,仔猪肠道健康营养调控的微生物组学研究(30810103909),2009.1-2012.12。  
(6)江苏省自然科学基金重点项目,改善反刍动物乳脂质量的营养调控机制研究(BK2007721),2007.7 – 2010.6。  
(7)国家自然科学基金重点项目,瘤胃甲烷形成与调控的微生物学和营养代谢基础(30530560),160万,2006.1- 2009.12。  
(8)国家重大基础计划项目(973):畜禽肉品质性状形成的代谢与调控机理(2004CB117500),课题4胃肠道结构与功能的发育规律及其调节(2004CB117500-4),2004.9 - 2009.8.31,参加。  
论文论著:
1)Dai ZL, Zhang J, Wu G, Zhu W-Y*, 2010. Utilization of amino acids by bacteria from the pig small intestine. Amino Acids, 39 (5): 1201-1215.   
2)Dai ZL, Wu G, Zhu W-Y*, 2011. Amino acid metabolism in intestinal bacteria: links between gut ecology and host health. Frontier in Bioscience 16, 1768-1786.
3)Mao SY*, Yang CF, Zhu W-Y, 2011.Phylogenetic analysis of methanogens in the pig feces. Current Microbiology, 62:1386–1389 (DOI 10.1007/s00284-011-9873-9)  
4)Jin W, Cheng Y-F, Mao S-Y, Zhu W-Y*, 2011. Isolation of natural cultures of anaerobic fungi and indigenously associated methanogens from herbivores and their bioconversion of lignocellulosic materials to methane. Bioresource Technology, (DOI: 10.1016/j.biortech.2011.06.026)
5)Dai ZL, Xi-Long Li, Peng-Bin Xi, Jing Zhang, Guoyao Wu, Zhu W-Y*, 2011. Metabolism of select amino acids in bacteria from the pig small intestine. Amino Acids, proofed, DOI: 10.1007/s00726-011-0846-x)   
6)Dai ZL, Xi-Long Li, Peng-Bin Xi, Jing Zhang, Guoyao Wu, Zhu W-Y*, 2011. Regulatory role for L-arginine in the utilization of amino acids by pig small-intestinal bacteria. Amino Acids, proofed, DOI: 10.1007/s00726-011-1067-z)
7)Huang RH, Qiu XS, Shi FX, Hughes CL, Lu ZF, Zhu W Y*. 2010. Effects of dietary allicin on health and growth performance of weanling piglets and reduction in attractiveness of faeces to flies. Animal, 5( 2) 304-311
8)Pei CX, Mao SY, Cheng YF, Zhu W-Y*, 2010. Diversity, abundance and novel 16S rRNA gene sequences of methanogens in rumen liquid, solid and epithelium fractions of Jinnan cattle. Animal, 4(1):20–29
9)Sun YZ, Mao SY, Zhu W-Y*. 2010. Rumen chemical and bacterial changes during stepwise adaptation to a high concentrate diet in goats. Animal, 4(2):210–217
10)Cheng YF, Edwards J E., Allison G G., Zhu W-Y* and Theodorou M K., 2009. Diversity and activity of enriched ruminal cultures of anaerobic fungi and methanogens grown together in consecutive batch culture. Bioresource Technology, 100 (2009) 4821–4828. 
11)Lu Y, Sarson AJ, Gong J, Zhou H, Zhu W-Y, Kang Z, Yu H, Sharif S, Han Y. Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens. Clinical and Vaccine Immunology, 2009, 16(11):1639-1647.
12)Iqbal MF, Zhu W-Y*, 2009. Characterization of newly isolated Lactobacillus delbrueckii –like strain MF-07 isolated from chicken and its role in isoflavone biotransformation. FEMS Microbiology Letters, 291 (2): 180-187, FEB 2009 
13)Iqbal MF, Zhu W-Y*, 2009. Bioactivation of flavonoid diglycosides by chicken cecal bacteria. FEMS Microbiology Letters, 2009, 295, 30-41.
14)Cheng YF, Mao SY, Liu JX, Zhu WY*, 2009.  Molecular diversity analysis of rumen methanogenic Archaea from goat in eastern China by DGGE methods using different primer pairs. Letters in Applied Microbiology, 2009, 48(5):585-592.
15)Zhou, W, Wang, GJ, Han, ZK, Yao, W,   Zhu, WY. 2009. Metabolism of flaxseed lignans in the rumen and its impact on ruminal metabolism and flora. Animal Feed Science and Technology, 150 (1-2): 18-26.
16)Zhou, W, Han, ZK, Zhu, WY, 2009. The metabolism of linseed lignans in rumen and its impact on ruminal metabolism in male goats. Journal of Animal and Feed Science, 18 (1): 51-60 2009
17)Su Y, Yao W, Perez O, Smidt H, Zhu W-Y*, 2008. Changes in abundance of Lactobacillus spp. and Streptococcus suis in stomach, jejunum and ileum of piglets after weaning. FEMS Microbiology Ecology, 66:546-555.
18)Yu ZT, Yao W, Zhu WY*, 2008. Isolation and identification of equol-producing bacterial strains from cultures of pig faeces. FEMS Microbiol Lett 2008, 282:73–80.
19)Su Y, Yao W, Perez-Gutierrez ON, Smidt H, Zhu WY*.2008. 16S ribosomal RNA-based methods to monitor changes in the hindgut bacterial community of piglets after oral administration of Lactobacillus sobrius S1. Anaerobe, 14(2): 78-86. 
20)Mao SY, Zhang G, Zhu WY*, 2008. Effect of disodium fumarate on ruminal metabolism and rumen bacterial communities in goat as revealed by denaturing gradient gel electrophoresis analysis of 16S ribosomal DNA. Animal Feed Science and Technology, 140 (2008) 293–306.
21)Mao SY, Zhang G, Zhu WY*, 2008. Effect of disodium fumarate on ruminal metabolism and rumen bacterial communities in goat as revealed by denaturing gradient gel electrophoresis analysis of 16S ribosomal DNA. Animal Feed Science and Technology, 2008, 140: 293–306.
22)Iqbal MF, Cheng YF, Zhu WY*, Zeshan B, 2008. Mitigation of ruminant methane production: current strategies, constraints and future options. World J Microbiol Biotechnol, 24:2747-2755.
23)Sun YZ, Mao SY, Yao W, Zhu WY*. 2008. DGGE and 16S rDNA analysis reveals a highly diverse and rapidly colonising bacterial community on different substrates in the rumen of goats. Animal, 2008, 2 (3): 391–398
24)Guo, YQ, Liu, JX, Lu, Y, Zhu, WY, Denman, SE, McSweeney, CS, 2008. Effect of tea saponin on methanogenesis, microbial community structure and expression of mcrA gene, in cultures of rumen micro-organisms. Letters in Applied Microbiology, 47(5):421-426.
25)Zhang, CM, Guo, YQ, Yuan, ZP, Wu, YM, Wang, JK, Liu, JX, Zhu, WY. 2008. Effect of octadeca carbon fatty acids on microbial fermentation, methanogenesis and microbial flora in vitro. Animal Feed Science and Technology, 146(3-4):59-269.
26)Mao SY, Zhu WY*, Wang QJ, Yao W. 2007, Effect of daidzein on in vitro fermentation of micro-organisms from the goat rumen. Animal Feed Science and Technology, 136:154-163.
27)Mao SY, Zhang G, Zhu WY*, 2007, Effect of disodium fumarate on in vitro rumen fermentation of different substrates and rumen bacterial communities as revealed by denaturing gradient gel electrophoresis analysis of 16S ribosomal DNA. Asia-Australian Journal of Animal Sciences, 20 (4): 543-549.
28)Liu W, Mao SY, Zhu WY*, 2007. Impact of tiny miRNAs on cancers. World Journal of Gastroenterology, 13(4):497-502.
29)Yu QH, Dong SM, Zhu WY, Yang Q, 2007. Use of green fluorescent protein to monitor Lactobacillus in the gastro-intestinal tract of chicken. FEMS Microbiology Letters, 275 (2): 207-213.
30)Wang HF, Zhu WY, Yao W, Liu JX, 2007. DGGE and 16S rDNA sequencing analysis of bacterial communities in colon content and feces of pigs fed whole crop rice. Anaerobe 13: 127-133.
31)  Li MY, Zhou GH, Xu XL, Li CB, Zhu WY.Changes of bacterial diversity and main flora in chilled pork during storage using PCR-DGGE. Food Microbiology, 2006, 23: 601-611.

32)Zhu WY*, Mao SY, Liu JX, Cheng YF, Iqbal MF, Wang JK, 2007. Diversity of methanogens and their interactions with other microorganisms in methanogenesis in the rumen. Plenary Paper, Proceedings of the 7th International Symposium on the Nutrition of Herbivores, pp 125-139,   Beijing  , September 17 – 22, 2007.
33)Zhu WY*, Iqbal M F, Cheng YF, Liu JX, Mao SY, 2008. Rumen methanogenesis and nutritional approaches to the mitigation of ruminant methane. Invited paper, The 13th Animal Science Congress of the Asian – Australasian Association of Animal Production Societies, International Symposium: ”Recent Advances in Ruminant Nutrition”, pp 33-40,  2008/9/22   
34)Zhu WY*, Mao SY, Cheng YF, Liu JX, Wang JK, 2009. Rumen microbial communities involved in methanogenesis and nutritional strategies to mitigate. Invited Keynote Speech: The 7th Korea-Japan-China Joint symposium on Rumen Metabolism and Physiology,  2009/8/5 .  
35)Han ZK, Wang GJ, Yao W, Zhu WY*. 2006. Isoflavonic phytoestrogens - new prebiotics for farm animals: a review on research in China. Current Issues in Intestinal Microbiology, 7:53-60.
36)毛胜勇,王新峰,朱伟云,2010. 体外法研究延胡索酸二钠对瘤胃微生物发酵活力及甲烷产量的影响。草业学报,19(2):69-75。
37)毛胜勇,龙黎明,朱伟云,2010. 体外研究反刍兽新月形单胞菌及与酵母联用对瘤胃微生物发酵的影响。草业学报,19(8):176-186。
38)陆扬,姚文,苏勇,朱伟云*, 2010. 大豆苷元对断奶仔猪胃肠道发育的影响. 南京农业大学学报,33(2):91-95.
39)成艳芬,朱伟云*,2009. ARISA方法研究产甲烷菌共存及去除条件下瘤胃真菌多样性变化。微生物学报,2009, 49(4):504-511.
40)杭苏琴,戴兆来,朱伟云*,2009,甘露寡糖对纯培养和共培养的乳酸杆菌体外生长的影响。微生物学通报,2009,36(1):51-56.
41)于卓腾,姚文,朱伟云*,2009,体外培养发现二花脸猪粪样菌群具有降解大豆黄酮产生雌马酚的能力。南京农业大学学报,2009,32(1):164-167。
42)刘相玉,毛胜勇,朱伟云*,2009,高精料日粮条件下酵母培养物对瘤胃细菌体外发酵的影响。动物营养学报,2009,21(2):199-204.
43)龙黎明,毛胜勇,苏勇,朱伟云,一株瘤胃源乳酸利用菌的分离鉴定及其体外代谢特性研究。微生物学报,2008,48(12):1571-1577。
44)苏勇,姚文,朱伟云*,代表性差异分析比较两株来自不同地区的猪源Lactobacillus 菌株。微生物学报,2008,48(5):1~6。
45)戴兆来,董红军,林勇,黄瑞华,朱伟云*,合生元组合筛选及对仔猪生产性能和腹泻的影响。南京农业大学学报,2008,31(2):81-85。
46)裴彩霞, 毛胜勇, 朱伟云*,晋南牛瘤胃中古菌分子多样性的研究。微生物学报,2008,48(1):8-14。
47)俞晓辉,姚文,施学仕,朱伟云,大豆发酵蛋白替代鱼粉对断奶仔猪生产性能和肠道主要菌群的影响。动物营养学报,2008,20(1):46-51。
48)罗玉衡,朱伟云*,2007,消化道微生物区系与肥胖关系的研究进展。微生物学报,47(6):1115-1118。
49)刘威,朱伟云*,姚文,毛胜勇,2007,一株乳酸利用、丁酸产生菌的分离与鉴定及代谢特性的初步研究。微生物学报,47(3):435-440。
50)张耿,朱伟云*,刘相玉,毛胜勇,2007,延胡索酸二钠对瘤胃微生物体外发酵不同饲料成分的影响。草业学报,16:112-117。
51)于卓腾 姚 文 毛胜勇 朱伟云*,2007,黄豆苷元对仔猪肠道微生物区系的影响。营养学报,29(1):82-86。
52)姚光国,姚文,陆扬,朱伟云*,2007,乳酸菌肽聚糖部分免疫增强作用的研究。微生物学通报,34(1):105-107。
53)成艳芬,毛胜勇,裴彩霞,刘建新,朱伟云*,共存于厌氧真菌分离培养液中瘤胃甲烷菌的检测及其多样性分析。微生物学报,2006,46(6):879-883。
54)孙云章,毛胜勇,姚文,朱伟云*,2006,不同精粗比底物下瘤胃真菌和纤维降解细菌共培养发酵特性及菌群变化。微生物学报,46(3):422-426。
55)姚文,朱伟云*, 毛胜勇,2006,16S rDNA技术跟踪分析新生腹泻仔猪粪样细菌区系的变化。微生物学报,45(1):150-154。

奖励及荣誉:
1)发明专利:一种芽孢乳杆菌及其生产的活菌制剂。专利号:ZL 200510038893.X (授权公开日: 2007年6月20日);  
2)国家发明专利受理一项:绞股蓝皂甙用于减少动物瘤胃内甲烷产生的方法。受理号:201010248023.6   
3)国家发明专利受理一项:阿卡波糖在制备反刍动物的药物或饲料中的应用。受理号:201010538758.2  
4)成果鉴定:仔猪肠道微生物区系研究及芽孢乳杆菌S1研制。苏科鉴字【2004】第1308号。鉴定形式:会议鉴定。组织鉴定单位:江苏省科技厅。鉴定日期:2005年1月29日 。  
5)研究生朱崇淼硕士学位论文:产木聚糖酶厌氧真菌的分离及其营养特性的研究,获得南京农业大学优秀论文奖。(2003年)  
6)研究生论文:瘤胃厌氧真菌对木质素含量不同底物附着及发酵特性研究。获得第五届全国畜牧兽医青年科技工作者学术研讨会,中国畜牧兽医学会提名奖。2004  
7)研究生成艳芬博士学位论文:厌氧真菌与产甲烷菌在瘤胃甲烷产生中的动力学研究,获江苏省优秀博士论文奖(2010年)  
8)2011年1月25日,“家畜胃肠道微生物功能及其调控研究”获教育部“自然科学奖”二等奖,第一完成人。