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姓  名:
石放雄
性  别:
职  称:
教授、博士生导师
最高学历:
博士
毕业院校:
浙江农业大学
专业领域:
动物遗传育种与繁殖,动物繁殖营养学
联系方式:
E-mail:fxshi@njau.edu.cn Tel:025-84399112
研究方向:
动物生殖生理与调控,动物繁殖与营养调控,生殖系统的细胞信号传导等。
参加学术团体及任职情况:
1.家畜繁殖学研究室主任,2.全国中文核心期刊《畜牧与兽医》杂志社主编,3.《The Open Andrology Journal》编委,4.《Journal of Animal Science Advance》编委,5.江苏省“333高层次人才培养工程”中青年科学技术带头人,6.学校“133优秀学科带头人”,7.南京市江宁区科技咨询委员会专家委员,8.中国畜牧兽医学会期刊编辑学分会常务理事。
承担项目:
不详
论文论著:
(1)SCI杂志
1)Liu W, Shi F, Lu L, Zhang C, Liu Y, Zhang J, Tao Z, Shen J, Li G, Wang D, Li J, Tian Y. Effects of linoleic acid and eicosapentaenoic acid on cell proliferation and lipid-metabolism gene expression in primary duck hepatocytes. Mol Cell Biochem. 2011; 352(1-2):19-24.
2)Liu W, Lai S, Lu L, Shi F, Zhang J, Liu Y, Yu B, Tao Z, Shen J, Li G, Wang D, Li J, Tian Y. Effect of dietary fatty acids on serum parameters, fatty acid compositions, and liver histology in Shaoxing laying ducks. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2011; 12: 736-743.
3)Huang P, Zhou Z, Huang R, Zhou B, Wei Q, Shi F. Age-dependent expression of forkhead box O proteins in the duodenum of rats. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2011; 12: 730-735.
4)Zhang W, Shi F. Do genetically modified (GM) crops affect animal reproduction? A review of the ongoing debate. Animal. 2011; 5: 1048-1059. 
5)Liu W, Zhang J, Lu L, Shi F, Niu D, Wang D, YU B, Tao Z, Shen J, Wang D, Tian Y. Effects of perilla extract on productive performance, serum parameters, and hepatic expression of lipid-related genes in Shaoxing ducks. British Poultry Science. 2011; 52(3):381-7.
6)Zhang W, Wei Q, Wang Z, Ding W, Wang W, Shi F. Cell-specific expression and immunolocalization of nitric oxide synthase isoforms and the related nitric oxide/cyclic GMP signaling pathway in the ovary of neonatal and immature rats. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2011; 12: 55-64.
7)Huang R, Qiu X, Shi F, Hughes CL, Lu Z, Zhu W. Effects of Dietary Allicin on Health, Growth Performance of Weanling Piglets, and Reduction in Attractiveness of Faeces to Flies. Animal. 2011; 5: 304-311.
8)Zhang F, Huang J, Li Q, Ju Z, Li J, Shi F, Zhong J, Wang C. Novel single nucleotide polymorphisms (SNPs) of the bovine STAT4 gene and their associations with production traits in Chinese Holstein cattle. African Journal of Biotechnology. 2010; 9:4003-4008.
9)Wang W, Liu H, Ding W, Gong Y, Chen J, Hutz RJ, Mao D, Shi F. Involvement of cell proliferation in the process of follicular atresia in the guinea pig. Tissue and Cell. 2010; 42: 234-241.
10)Wang W, Liu H, Tian W, Zhang F, Gong Y, Chen J, Mao D, Shi F. Morphologic observations and the classification criteria of atretic follicles in guinea pigs. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2010; 11: 307-314.
11)Zhou B, Liu H, Shi F, Wang J. MicroRNA expression profiles of porcine skeletal muscle. Animal Genetics. 2010; 41: 499-508. 
12)Wang H, Huang P, Lie T, Li J, Hutz RJ, Li K, Shi F. Reproductive toxicity of acrylamide-treated male rats. Reproductive Toxicology. 2010; 29: 225-230.
13)Ding W, Wang W, Zhou B, Zhang W, Huang P, Shi F, Taya K. Formation of primordial follicles and immunolocalization of PTEN, PKB and FOXO 3A  proteins in the ovary of fetal and neonatal pigs. Journal of Reproduction and Development. 2010; 56(1): 162-168.
14)Luo J, Tian Y, Tao Z, Yuan Q, Li G, Yuan A, Zou L, Lu L, Shi F. Regulatory expression of peroxisomeproliferator activated receptors genes during fatty liver formation in geese. Agricultural Sciences in China. 2010; 9(1):113-120.
15)Wang Z, Shi F, Jiang Y, Lu L, Watanabe G, Taya K. Changes of cyclic AMP levels and phosphodiesterase activities in the rat ovary. Journal of Reproduction and Development. 2007; 53(4):717-725. (PMID: 17380041).
16)Meng C, Shi F, Huang R, Liu G, Watanabe G, Taya K. Cellular localization of inhibin alpha-subunit, PKB/Akt and FoxO 3a  proteins in the ovary of minipigs. Journal of Reproduction and Development. 2007; 53(2): 229-236. (PMID: 17132910). 
17)Huang R, Shi F, Lei T, Song Y, Hughes CL, Liu G. Effect of the isoflavone genistein against galactose-induced cataracts in rats. Experimental Biology and Medicine. 2007; 232:118-125. (PMID: 17202592). 
18)Wang Z, Shi F. Phosphodiesterase 4 and compartmentalization of cyclic AMP signaling. Chinese Science Bulletin. 2007; 52:34-46.
19)潘玲梅,王恬,石放雄. 肌卫星细胞激活和补给的分子调控与肌肉疾病. 生物化学与生物物理进展 2006; 33(9):811-815.
20)Huo YJ, Wang T, Xu RJ, Macdonald S, Liu G, Shi F. Dietary insulin affects leucine aminopeptidase, growth hormone, insulin-like growth factor I and insulin receptors in the intestinal mucosa of neonatal pigs. Biology of the Neonate. 2006; 89:265-73. (PMID: 16479091).
21)Liu G, Shi F (equal contribution), Blas-Machado U, Yu R, Davis VL, Foster WG, Magoffin DA, Hughes CL. Dietary Galactose Inhibits GDF-9 Mediated Follicular Development in the Rat Ovary. Reproductive Toxicology 2006; 21:26-33. (PMID: 16105726).
22)李学斌, 谢 庄, 石放雄. FOXO 蛋白的修饰与细胞凋亡和癌变.生物化学与生物物理进展 2005; 32:600-606. 
23)Liu G, Shi F, Blas-Machado U, Duong Q, Davis VL, Foster WG, Hughes CL. Ovarian effects of high lactose diet in the female rat. Reproduction, Nutrition, Development 2005; 45:185-192. (PMID: 15954229). 
24)Wang T, Huo Y, Shi F, Xu R, Hutz RJ. Effects of Intrauterine Growth Retardation on Development of the Gastrointestinal Tract in Neonatal Pigs. Biology of the Neonate 2005; 88:66-72. (PMID: 15785017). 
25)Shi F, Perez E, Wang T, Peitz B, Lapolt PS. Stage and Cell-Specific Expression of Soluble Guanylyl Cyclase alpha and beta Subunits, cGMP-Dependent Protein Kinase I-alpha and I-beta, Cyclic Nucleotide-Gated Channel Subunit -1 in  the Rat Testis. Journal of Andrology 2005; 26:258-263. (PMID: 15713832). 
26)Shi F, Stewart RL, Perez E, Chen JY, LaPolt PS. Cell-specific expression and regulation of soluble guanylyl cyclase alpha and beta subunits in the rat ovary. Biology of Reproduction 2004; 70:1552-1561. (PMID: 14749300). 
27)Shi F, LaPolt PS. Relationship between FoxO1 protein levels and follicular development, atresia, and luteinization. Journal of Endocrinology 2003; 179:195-203. (PMID: 14596671).
28)Shi F, Petroff BK, Herath CB, Ozawa M, Watanabe G and Taya K. Serous cysts are a benign component of the cyclic ovary in the guinea pig with an incidence dependent upon inhibin bioactivity. Journal of Veterinary Medical Science 2002; 64(2):129-135. (PMID: 11913549). 
29)Akagi S, Shi F, Kaneko H, Nakanishi Y, Watanabe G, Tsonis CG and Taya K. Ovarian response and hormonal profiles in heifers after immunization and re-immunization against the inhibin alpha-subunit. Journal of Reproduction and Development 2002; 48(6): 599-605. 
30)Petroff BK, Gao X, Ohshima K, Shi F, Son D, Roby KF, Rozman KK, Watanabe G, Taya K and Terranova P. Effects of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) on serum inhibin concentrations and inhibin immunostaining during follicular development in female Sprague-Dawley rats. Reproduction Toxicology 2002; 16:97-105. (PMID: 11955940). 
31)Tohei A, Shi F, Ozawa M, Imai K, Takahashi H, Shimohira T, Watanabe G and Taya K. Dynamic changes in plasma concentrations of gonadotropin, inhibin, estradiol and progesterone in cows with ultrasound-guided follicular aspiration. Journal of Veterinary Medical Science 2001; 63:45-50. (PMID: 11217062).
32)Ozawa M, Shi F, Watanabe G, Suzuki AK and Taya K. Regulatory role of inhibin in follicle-stimulating hormone secretion and folliculogenesis in the guinea pig. Journal of Veterinary Medical Science 2001; 63: 1091-1095. (PMID: 11714024).
33)Shi F, Ozawa M, Komura H, Watanabe G, Tsonis CG, Suzuki AK and Taya K. Induction of superovulation by inhibin vaccine in cyclic guinea pigs. Journal of Reproduction and Fertility 2000; 118:1-7. (PMID: 10793620) 
34)Shi F, Mochida K, Ogura A, Matsuda J, Suzuki O, Watanabe G, Hutz RJ, Tsonis CG, Suzuki AK and Taya K. Follicle selection in guinea pigs with active immunization against inhibin alpha-subunit. Life Sciences 2000; 66:2489-2497. (PMID: 10894091).
35)Shi F, Mochida K, Suzuki O, Matsuda J, Ogura A, Tsonis CG, Watanabe G, Suzuki   AK and Taya K. Development of superovulated embryos in guinea pigs with active immunization against inhibin alpha-subunit. Endocrine Journal 2000; 47(4): 451-459. (PMID: 11075726).
36)Shi F, Watanabe G, Trewin AL, Hutz RJ and Taya K. Localization of ovarian inhibin/activin subunits in follicular dominance during the estrous cycle of guinea pigs. Zoological Science 2000; 17(9):1311-1320.
37)Shi F, Mochida K, Matsuda J, Ogura A, Suzuki O, Ozawa M, Watanabe G, Suzuki AK and Taya K. Ovarian localization of immunoglobulin G and inhibin alpha-subunit in guinea pigs following passive immunization against the inhibin a-subunit. Journal of Reproduction and Development 2000;46:293-299. 
38)Shi F, Ozawa M, Komura H, Yang P, Trewin AL, Hutz RJ, Watanabe G and Taya K. Secretion of ovarian inhibin and its physiologic roles in the regulation of follicle-stimulating hormone secretion during the estrous cycle of the female guinea pig. Biology of Reproduction 1999; 60:78-84. (PMID: 9858489).
(2)Medline杂志:
39)曹文; 黄攀; 张磊; 吴红照; 张郡; 石放雄. 急性热应激对性成熟雄性小鼠睾丸、附睾、输精管中热休克蛋白70表达的影响.中华男科学杂志,2009, 15 (3) : 2002-206.
40)Wang Z, Jiang Y, Lu L, Huang R, Hou Q, Shi F. Molecular mechanisms of cyclic nucleotide-gated ion channel gating. Journal of Genetics and Genomics, 2007; 34(6):477-485. (PMID:17601606)  
41)王皓,葛津瑶,周振琪,王正朝,石放雄。口服丙烯酰胺对雄性大鼠生长发育及生殖机能的影响。中华男科学杂志,2007,13(6):492-497. (PMID: 17615970).
(3)其他杂志:
43)张宝乐,李国勤,章鹤,沈军达,李进军,陶争荣,陈奕春,王德前,陈文标,石放雄,卢立志。鸭BLVRA基因cDNA克隆及其在输卵管子宫部的mRNA表达量与青壳性状的相关性分析。畜牧兽医学报,2010,41(9):1082-1089. 
44)张宝乐,任晋东,李国勤,石放雄,卢立志。鸭蛋壳颜色定量测定与统计学分析。浙江大学学报( 农业与生命科学版) ,2010, 36( 5) : 573~ 577.
45)方天,丁威,张伟,周波,石放雄。猪卵巢发育的组织学观察及磷酸二酯酶3A的表达研究。南京农业大学学报,2010,33 (6): 101-104.
46)杨岳,王长法,黄金明,仲跻峰,石放雄。奶牛乳腺炎抗性相关候选基因研究进展。家畜生态学报,2010,31(4):101-104. 
47)贾红敏,卢立志,石放雄,李国勤。动物TLR4基因多态性及其抗病相关性研究进展。生命科学,2010,22(6):546-550.
48)刘玮孟,卢立志,石放雄,张静,弓彦,田勇。日粮不同种类脂肪酸对青壳Ⅱ号蛋鸭蛋黄胆固醇含量和肌肉pH值的影响。饲料工业,2010;31(23):18-20. 
49)黄攀,傅春泉,茆达干,石放雄。雌二醇与孕酮奶样纸片酶免法的建立及应用。畜牧与兽医,2010;42(7):5-7.
50)陆燕,林波,王恬,石放雄,刘建新. 大蒜油对体外瘤胃发酵甲烷生成和微生物区系的影响. 动物营养学报,2010,22(2):386-392.
51)潘玲梅; 石放雄; 曹文; 张莉莉; 王恬. 一氧化氮信号通路关键酶在猪肌肉系统中的定位.南京农业大学学报,2010,33 (2): 79-82.
52)邹丽丽; 陶争荣; 张存; 李国勤; 沈军达; 任晋东; 石放雄; 卢立志. HSP70在急性热应激蛋鸭脾脏表达变化的研究.中国畜牧杂志,2010,46(30):6-9.
53)曹文,潘玲梅,田谷一善,石放雄.磷酸二酯酶在卵母细胞成熟中的作用.细胞生物学杂志, 2009,31(4): 497-502. 
54)陆燕; 黄攀; 王恬; 石放雄。日粮多不饱和脂肪酸对家畜繁殖性能的影响。中国畜牧兽医,2009,36(9):23-26. 
55)王皓; 李健; 石放雄. 丙烯酰胺的生殖毒性及其影响机理. 畜牧与兽医,2009,41(3):96-99. 
56)陆燕; 王恬; 石放雄; 林波. 大蒜素对瘤胃发酵和甲烷产量的影响. 中国饲料,2009, (10):11-13.
57)张芬芬; 王长法; 黄金明; 仲跻峰; 石放雄. 催乳素受体的研究进展. 家畜生态学报, 2009, 30(3):6-9.
58)严明; 蒋永清; 石放雄. 奶牛脂肪肝的病理学及防治研究进展. 畜牧与兽医, 2009, 41(2):92-95. 
59)邹丽丽; 陶争荣; 沈军达; 任晋东; 石放雄; 卢立志。急性热应激对蛋鸭内脏组织HSP70表达的影响。浙江农业学报,2009,21(4) :332~334. 
60)罗锦标; 田勇; 陶争荣; 袁青妍; 李国勤; 王德前; 原爱平; 邹丽丽; 卢立志; 沈军达; 石放雄。PPAR基因在鹅肥肝形成中的可调节性表达。中国农业科学,2008,41(10):3270-3276. 
61)黄攀; 陆燕; 茆达干; 石放雄. 日粮多不饱和脂肪酸对畜禽肉品质的影响. 畜牧与兽医, 2008, 40(12): 93-95.
62)邹丽丽; 王沼智; 李国勤; 陶争荣; 沈军达; 杨仲一; 王德前; 田勇; 原爱平; 石放雄; 卢立志. 不同饲养模式下热应激对蛋鸭的影响. 畜牧与兽医,2008, 40(5):45-47. 
63)王正朝,钟灵秀,郭宁,张磊,石放雄。长期饮酒对哺乳动物卵巢功能及其eCG反应性的影响。南京农业大学学报,2008,31:155-158. 
64)殷定忠; 庞训胜; 王正朝; 蔡治华; 石放雄。免疫与未免疫鸡感染MDV后血液部分指标及血浆MDA含量与SOD活性的动态变化。中国兽医学报,2008;28(9):1047-1050。
65)刘宇涛; 夏薇; 韦笑天; 马维军; 周聪; 王伟; 石放雄。脱氢表雄酮诱导大鼠多囊卵巢综合征的研究。动物医学进展,2008;29(9):27-29。
66)杨郑州; 田伟; 王正朝; 石放雄. 长期饮酒对哺乳动物免疫器官生长发育的影响. 家畜生态学报,2008,29(4):65-67.
67)罗锦标; 袁青妍; 陶争荣; 田勇; 李国勤; 王德前; 原爱平; 邹丽丽; 卢立志; 沈军达; 石放雄. 填饲前后鹅PPARs基因组织表达特性的研究. 中国家禽, 2008,30(15):24-27. 
68)李开桢; 曲亮; 黄瑞华; 石放雄; 邱新深; 周波; 刘红林; 王林云. mRNA差异显示技术的优化及其在苏淮猪育种中的应用. 畜牧与兽医, 2008,40(10):97-101. 
69)殷定忠; 蔡治华; 王正朝; 庞训胜; 杨峰; 石放雄。硒在雏鸡抗MDV感染中的作用及其机制研究。中国兽医杂志,2008;44(5):26-27。
70)李健,石放雄。PDE5参与平滑肌功能调节的机制。细胞生物学杂志,2008,30:431-434. 
71)曹文,潘玲梅,蒋永清,孟春花,李键,田谷一善,石放雄。螯合细胞外钙离子调控体外培养的大鼠卵巢颗粒细胞成熟的机制。细胞生物学杂志,2008,30:234-238.
72)张高振,吴红照,方唯威,张郡,申玲玲,谭忠银,石放雄。长期饮酒对小鼠生长发育及其睾丸功能的影响。中国男科学杂志,2008,22(1):3-6。
73)张聪聪,卢立志,石放雄。载脂蛋白A5低甘油三酯效应的机理。中国动脉硬化杂志,2007:15(12):964-968。
74)Wang Z, Shi Q, Shu G, Shi F. Immunohistochemical studies on ovarian follicular cells of Chinese Holstein Cows. Chinese Jjournal of Histochemistry and Cytochemistry, 2007, 16(5): 521-526. 
75)曹文,石放雄。PI-3K/Akt通路的下游因子磷酸二酯酶3B及其临床研究。细胞生物学杂志,2007,29(6):800-804.
76)宋亚军,葛津瑶,梁国旗,檀传艳,王莉莉,石放雄。高频饮用牛奶和葡萄糖对雌性大鼠生殖机能的影响。家畜生态学报,2007,28(4):53-56.
77)罗锦标,卢立志,石放雄。日粮胆碱对鹅肥肝形成的影响。畜牧与兽医,2007,39(4):36-38。
78)周振琪,王恬,石放雄。FOXO转录因子调控哺乳动物的细胞周期和凋亡。细胞生物学杂志,2007,29(2):187-190。 
79)王正朝,石放雄。 PDE4与cAMP信号区域化.科学通报2006; 51:2577-2586. 
80)王正朝,罗锦标,石放雄。环核苷酸门控离子通道与疾病发生。动物医学进展,2006,27(8):1-4。 
81)王正朝,黄瑞华,潘玲梅,李学斌,石放雄。环核苷酸门控离子通道的结构、功能及活性调节。中国生物化学与分子生物学报,2006, 22:282-288。 
82)王正朝,庞训胜,潘晓燕,王锋,石放雄。微卫星技术在体细胞克隆动物研究中的应用。家畜生态学报,2006,27(4):14-17。 
83)潘玲梅,周振琪,王恬,石放雄。一氧化氮对动物卵巢细胞中功能蛋白基因表达的调节。家畜生态学报,2006,27(2):92-96。
84)李学斌, 谢庄, 石放雄。FOXO蛋白在动物细胞的分化,增殖,免疫,衰老调节中的作用。中国临床康复,2006,10:158-162。 85)Wang Z, Xu W, Pang X, Shi F, Wang F. Identification methods of embryonic stem cells. Chinese Journal of Clinical Rehabilitation. 2006; 10: 187-189 (王正朝,许卫华,庞训胜,石放雄,王锋。胚胎干细胞的鉴定方法。中国临床康复,2006,10:187-189). 
86)周振琪,潘玲梅,王恬,石放雄。环鸟苷酸对卵巢细胞功能的调控。细胞生物学杂志,2005, 27:603-606.
(4)书本章节:
1)Zheng-chao Wang, Fang-xiong Shi. Ion Channel Book, Part 2: Individual Ion Channel Characteristics: Intracellular Ligand\Environment-Gated Ion Channels. Ceri. H. Davies and James. N. Kew (Editors). Oxford University Press, UK., 2009.
2)石放雄(副主编).《动物生物技术》(普通高等教育“十一五”规划教材),蒋思文主编,科学出版社,北京,2009. 
(5)会议论文:
1) Shi F. Cellular localization of the FoxO 3a  protein in the ovary and changed concentrations of intracellular calcium during maturation of granulosa cells in vitro in the pig. The International Symposium on Advances in Modern Biology, Theme: Life Sciences in 21st century, Sept. 11-13, 2009, Nanjing ,  China (Plenary session).
2) Shi F. Regulatory expression of FoxO 3a  proteins in different size of follicles and changed concentrations of intracellular calcium during maturation of granulosa cells in vitro in the pig.5th Annual Conference of Asian Reproductive Biotechnology Society, Nov. 27-29, 2008(Plenary session, 第五届亚洲繁殖生物技术大会特邀报告,云南昆明)。
3) 王正朝,石放雄.第二信使cAMP/cGMP信号通路元件蛋白在中国荷斯坦奶牛卵巢中的定位研究。中国畜牧兽医学会动物繁殖学分会第十四届学术研讨会,2008年8月,青岛。
4) 孟春花,李健,张芬芬,方天,田伟,石放雄。不同直径猪卵泡中FoxO 3a 转录因子和细胞内钙离子对卵巢颗粒细胞的调节,中国畜牧兽医学会动物繁殖学分会第十四届学术研讨会,2008年8月,青岛。 
5) Wang Z, Shi F. Role of phosphodiesterase in cyclic nucleotide signaling during ovarian follicular development in the rat.第一届中华医学会生殖医学分会-中国动物学会生殖生物学会联合年会,2007年4月,杭州。
5) Wang X, Huang K, Shi F (Managing Editor). Proceeding of International Conference on Avian Nutrional and Metabolic Disorders. April 14-17, 2006, Nanjing ,  China. 
6) 石放雄。通过人工受精和胚胎移植传播的奶牛疾病。第2届中国奶牛发展大会大会专题报告,内蒙古包头,2006年6月,pp119-126. 
7) 石放雄。与雌激素有关的功能蛋白基因表达和调控。中国地方猪种保护与利用协作组第3次年会暨学术研讨会,2005年11月,江西玉山。
8) 李学斌,王林云,谢庄,石放雄。FoxO1蛋白水平与磷酸化水平。第一届中国养猪生产和疾病控制技术大会--2005中国畜牧兽医学会学术年会论文集,2005年4月,山东济南,pp206-210. 
9) 石放雄。环鸟苷酸对卵巢细胞功能的调控。中国畜牧兽医学会动物繁殖学分会学术年会,2004年8月,浙江宁波。
奖励及荣誉:
不详